On-chip Robotics for Biomedical Innovations
51/70 Motivation: Investigation of Microorganisms

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Now, let me introduce how important the mechanical stimulation to microorganism. This figure shows an example of our target, Pleurosira laevis called P. laevis. P. laevis living in fresh water is a cylindrically-shaped single cell with a glass structure. This cell has a unique behavior, when a single cell gets the stimulation, the chloroplasts move to around the nucleus, as shown in this picture. Furthermore, this agglomeration is transmitted to other connected cells and also unconnected cells. However, this mechanism with chemical reaction has not been fully understood yet. Investigation of this function is really important to understand the interaction and growth factor of cells. Here, there are two important points to evaluate the relationship between the mechanical stimulation and response of cell. The first thing is that we should measure the amount of applied stimulation to cell as an applied force. Another thing is that after stimulation, we should keep the experimental condition to observe the chemical reaction of cell precisely. Therefore, the measurement system for microorganism must satisfy in both force sensing and environmental control.